2 tablespoons Mexican hot sauce (like Cholula or Tapatio)
sliced pepperjack cheese
hamburger buns
chipotle mayonnaise
lots of sliced jalapenos
Thoroughly mix ground beef with the taco seasoning and hot sauce in a large bowl. Form into 9 to 12 patties. Grill for 20 or so minutes, flipping once and applying cheese after 10 minutes. Take a bun, and add one layer of jalapenos. Apply mayonnaise, so that it flows into the gaps between and inside the jalapenos (so it won't squirt out when you eat it). Apply 1 cooked patty, and pile on as many jalapenos as you can stomach, and maybe add more hot sauce if desired. Eat.
I had an idea for this recipe over a year ago, but it took two or three iterations to get just right. When I did, it tasted exactly the way I wanted it. To me, this is what a southwestern burger should be, and I will be dissatisfied with other substitutes.